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Fact Sheet
Superficial thrombophlebitis
- occurs when there is inflammation and clot in a surface vein

Superficial thrombophlebitis *


Overview

Superficial thrombophlebitis occurs when there is inflammation and clot in a surface vein. Inflammation in the vein often occurs after an injury (e.g. a knock to the vein) but may occur without any injury.

What are the symptoms of thrombophlebitis?

Inflammation in the vein often causes symptoms of pain and swelling around the vein. Often a ropey cord (which is the vein with clot within it) can be felt and is usually tender.

Is superficial thrombophlebitis dangerous?

In itself, superficial thrombophlebitis is not dangerous. It is important however to ensure that the clot has not grown to involve other veins (deep veins). Clot that involves deep veins can often grow and even “travel” to other parts of the body (e.g. the lungs). Clot that only involves the surface (superficial veins) rarely if ever travels to other parts of the body.

What tests need to be done for superficial thrombophlebitis?

An ultrasound of the vein needs to be performed to show where the clot is within the vein and to rule out other veins being involved. Ultrasounds are harmless and not painful.


Treatment & Management

What is the treatment of superficial thrombophlebitis?

The treatment of superficial thrombophlebitis depends on the cause and the type and severity of the symptoms present.

Anticoagulation

In superficial thrombophlebitis of the legs, a short course (4 weeks duration) a medication that reduces the blood clotting power of the body is generally recommended. This treatment has been shown to reduce the symptoms and to also prevent clots growing and involving the deep veins. The use of this medication has side effects however and this should be discussed with your doctor.

Compression & Anti-inflammatory Medications

Other treatments available for superficial thrombophlebitis include compression bandages and oral medications called anti-inflammatory medications (e.g. Voltaren).

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How common is Hereditary Spherocytosis (HS)?

HS is relatively common – around 1 person in every 5000 people has HS (around 800 people in Melbourne; population 4 million).

0

in 5000 people has HS

Which is the same as

0

people in Melbourne

0

population of Melbourne*


What does having HS mean?

There are three main common problems associated with having HS:

01.

Anaemia

– this occurs because the red cells break down more quickly

02.

Jaundice

– when red cells break down they release a pigment called bilirubin which appears as a yellow colour in the skin and the eyes. Over a long period of time, the problem of jaundice can be associated with gall stones.

03.

Increase in the size of the spleen

– this is the site of the red cells breaking down. The spleen is a blood filter and some of the red cells can get caught up in the spleen

There is another uncommon potential problem for people who have Hereditary Spherocytosis associated with a viral infection called “Slapped cheek”. Slapped cheek is caused by a virus called Parvovirus which can infect bone marrow cells and put the red cell producing cells “to sleep”. Because patients with HS need the bone marrow to be rapidly replacing the fragile red cells, this infection can cause a severe anaemia; patients can become very pale and sometimes even require blood transfusions. Fortunately this problem is uncommon.


Diagnosis

How is Hereditary Spherocytosis diagnosed?

HS is now diagnosed with a simple blood test. It is also important for a doctor to examine patients with HS to see if they are jaundiced or have an increase in the size of the spleen.


Treatment & Management

What do I need to do now that I (or my child) has been diagnosed with Hereditary Spherocytosis?

Most patients with HS do not need to do much about their condition at all. The bone marrow has the capacity to increase the number of red cells it produces many fold and is able to keep up replacing the fragile cells.

A few things may be helpful:

01.

Regular blood tests

– to check on the level of haemolysis

02.

Folate supplementation

An important vitamin necessary for the bone marrow to function properly is folate. Folate is found in green leafy vegetables. Most people get enough folate in their diet but getting extra folate (particularly in HS if there is significant haemolysis – red cell breakdown) is generally recommended.

03.

Ultrasounds to exclude gall stones

It may also be important to make sure children and adults are not developing gall stones – an ultrasound of the gall bladder after that age of 5 years of age every 3 – 5 years there after, is the current recommendation.

Will I (or my child) need a splenectomy?

Removing the spleen (splenectomy) has been used a lot in the past in the treatment and management of patients with HS; it stops the red cells from breaking down and solves the problems of HS.

Removing the spleen has problems however – the spleen is an important organ in the immune system and patients who do not have a spleen may be prone to getting serious infections. This risk is higher in younger children but may be less than previously expected because of newer vaccinations. It is now generally recommended to avoid splenectomy in children younger than 6 years and to ensure that children who may need a splenectomy have all the appropriate vaccinations.

Another approach for some of these young patients is to remove only a small part of the spleen – partial splenectomy. This is done in a few hospitals and there is some experience to say this may be very helpful for some patients.


Resources used to produce this information sheet.

  1. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic andThrombolytic Therapy. Chest. :401S-428S, 2004;126(3 Suppl).


Further Questions?

The information presented in this fact sheet is intended as a general guide only.

Patients should seek further advice and information about having superficial thrombophlebitis and their individual condition from their treating haematologist or doctor.

1000 563 Melbourne Haematology
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