CONSULTANT HAEMATOLOGIST
Professor Huyen Tran
MBBS (Hons) Master Clin Epi FRACP FRCPA
Huyen Tran is a senior haematologist, Head of Thrombosis and Haemostasis Services, and Director of the Haemophilia Treatment Centre at Alfred Health. He is a clinical Professor at the Australian Centre for Blood Diseases (ACBD), Central Clinical School, Monash University. He is Chair of the Clinical Trials group of The Thrombosis and Haemostasis Society of Australia and New Zealand (THANZ) and Chair of the Gene and Novel Therapies (GETS) committee, Australian Haemophilia Centres Directors’ Organisation (AHCDO)
He completed his medical degree at Monash University and his dual fellowships in Clinical & Laboratory Haematology at Monash and Melbourne Health in Melbourne. He spent two years at McMaster University, Canada pursuing clinical research in thrombotic disorders before returning to Australia to complete his Master of Clinical Epidemiology. In 2016 he spent months at Hospices Civils de Lyon, France exploring advances in congenital bleeding disorder therapies.
Practice Interests
Prof Tran’s focus is on clinical research in haematology with particular interests in the management of venous thromboembolism (VTE) and its complications, congenital haemophilia, rare bleeding disorders, immune platelet disorders and novel therapeutics, as well as obstetrics haematology. He has been a principal investigator in over 70 trials in these areas, has over 130 peer reviewed publications with >8300 citations. He supervises PhD candidates and advanced haematology trainees and has lectured widely in the Asia-Pacific region. He works with local, national and international advisory boards, and disease-specific advocacy groups to advocate for novel therapies to improve patient outcomes. He contributes to the World Health Organisation (WHO) and World Federation of Haemophilia (WFH) to improve care in low- and middle-income countries.
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Prof Tran adopts an evidenced based approach to clinical practice, applying what is the cutting edge in the field to improve standard of care. He prefers a clear, direct and honest approach in looking after his patients.
Practice Locations
Professor Huyen Tran consults privately in his rooms located within Monash Specialist Centre, Clayton.
TeleHealth appointments are available.
Monash Specialist Centre
Suite 10
212-220 Clayton Rd
Clayton VIC 3168
Tel: 03 9544 6448
Fax: 03 8610 2177
Hospital Accreditation
Clinical Interests Include:
Updated: September 2025
Languages Spoken (Other than English)
Vietnamese, French
Extended Profile
Professor Huyen Tran
– Key Research, Journal & Book Publications, Presentations &/or Awards
Selected Journal Publications (Recent)
- Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE. Vaccine-induced immune thrombotic thrombocytopenia (VITT) – update on diagnosis and management considering different resources: Response to Comment from Yamada et al. J Thromb Haemost. 2022 Feb;20(2):542-543
- Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE. Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources. J Thromb Haemost. 2022 Jan;20(1):149-156.
- Dix C, Tee A, McFadyen JD, Tran H. Acquired haemophilia A: Insight into treatment and outcomes from an Australian tertiary referral centre. Haemophilia. 2021 Dec 29. doi: 10.1111/hae.14481. Epub ahead of print.
- McFadyen JD, Sharma P, Moon MJ, Noonan J, Goodall E, Tran HA, Peter K. Activation of circulating platelets in vaccine-induced thrombotic thrombocytopenia and its reversal by intravenous immunoglobulin. Br J Haematol. 2022 Jan;196(1):234-237. doi: 10.1111/bjh.17750. Epub 2021 Aug 16.
- Hocking J, Chunilal SD, Chen VM, Brighton T, Nguyen J, Tan J, Ting SB, Tran HA. The first known case of vaccine-induced thrombotic thrombocytopenia in Australia. Med J Aust. 2021 Jul;215(1):19-20.e1. doi: 10.5694/mja2.51135. Epub 2021 Jun 11.
- Draxler DF, Zahra S, Goncalves I, Tran H, Hanafi G, Ho H, Keragala CB, Ilich A, Key NS, Myles PS, Medcalf RL. Tranexamic acid rapidly inhibits fibrinolysis, yet transiently enhances plasmin generation in vivo. Blood Coagul Fibrinolysis. 2021 Apr 1;32(3):172-179.
- Bui T, Bortz H, Corella C, Tran H AAA Stewardship: managing high-risk medications with dedicated Antimicrobial, Anticoagulation and Analgesic Stewardship programs. Journal of Pharmacy Practice and Research. In Press
- Oldenburg J, Tran HA, Peyvandi F, Núñez R, Trask P, Chebon S, Mahlangu JN, Lehle M, Jiménez-Yuste V, von Mackensen S. Health-related quality of life and health status in adolescent and adult people with haemophilia A without factor VIII inhibitors-A non-interventional study. Haemophilia. 2021 May;27(3):398-407. doi: 10.1111/hae.14270. Epub 2021 Feb 12.
- Stevens H, Peter K, Tran H, McFadyen J. Predicting the Risk of Recurrent Venous Thromboembolism: Current Challenges and Future Opportunities. J Clin Med. 2020 May 22;9(5):1582.
- Brennan Y, Parikh S, McRae S, Tran H. The Australian experience with switching to extended half-life factor VIII and IX concentrates: On behalf of the Australian Haemophilia Centre Directors’ Organisation. Haemophilia. 2020 May;26(3):529-535.
- Stevens HP, McFadyen J, Tran HA. Risk stratification of acute pulmonary embolism and determining the effect on chronic cardiopulmonary complications: The REACH Study. Thrombosis Haemostasis Open journal. 2020 4(1):E45-E50.
- Campbell S, Mason J, Hunt S, Prasad R, Ambrose H, Tran HA. Acquired haemophilia and haemostatic control with recombinant porcine FVIII. Int Med Journal 11 Feb 2020.
- Chelle P, Yeung CHT, Croteau, S Lissick S, Balasa V, Ashburner C, Young Shil Park Kyung, Bonanad S, Juan Eduardo Megias Vericat, Edginton A, Tran HA, Iorio A. Development and validation of a population pharmacokinetic model for Rurioctacog alfa pegol (Adynovate). A report on behalf of the WAPPS-Hemo investigators ad hoc subgroup. Clinical Pharmacokinetics 2019;1-12
- Valente M, Leung S, Wu P, Oh D, Tran HAM, Choi P. Acute ischemic stroke and TIA whilst on anticoagulants – outcomes in the era of Direct Oral Anticoagulants. Int Med J. ePub October 14, 2019.
- Singh J, Ong MD, Lim, M. Collecutt, E. Malan, P. Servadei, A. Wallis, G. Kelsey, S. Chunilal, H.A. Tran. Anti-Xa levels with enoxaparin calibrator can be used to exclude significant apixaban effect. Int J of Lab Hemat. ePub July 9, 2019
- Mezhov V, Campbell S, Powell A, Jain A, Tran HA. Pseudotumour in haemophilia A due to non-adherence: a Case report. Internal Medicine Journal. ePub September 11, 2019.
- T. Day, HA. Tran. Venous Thromboembolism: Applying guidelines in Primary Care. Medicine Today 2019; 20(7): 12-22.
- Stevens H, Tran HA, Gibbs H. Venous thromboembolism: current management. Aust Prescr. 2019 42(4): 123-6
- J. Singh, M. D. Ong, V. Ling, M. Lim, M. Collecutt, E. Malan, P. Servadei, A. Wallis, G. Kelsey, S. Chunilal, H.A. Tran. Inter-laboratory validation of apixaban levels in ex-vivo patient samples using a modified anti-Factor Xa assay. International Journal of Laboratory Hematology. ePub July 9, 2019.
- Draxler DF, Yep K, Hanafi G, Winton A, Maria Daglas, Ho H, Sashindranath M, Wutzlhofer LM, Forbes A, Goncalves I, Tran HA, Wallace S, Plebanski M, Myles P, Medcalf R. Tranexamic acid modulates the immune response and reduces postsurgical infection rates. Blood Advances 2019 3(10);1598-1609.
- Aubron C, McQuilten Z, Bailey M, Board J, Buhr H, Cartwright B, Dennis m< Forrest P, McIllroy D, Murphy D, Murray L, Pellegrino V, Pilcher D, Sheldrake J, Tran HA, Vallance S, Cooper J. Low-dose heparin versus therapeutic anticoagulation in patients undergoing extracorporeal membrane oxygenation – a randomised pilot trial. In press Critical Care Medicine.
- Campbell S, Parikh S, Tran HA. Complication rates of central venous access devices in patients with inherited bleeding disorders in Australia. Br J Haematol ePub 2019 April 2
- H. MacLachlan, H. P. Stevens, S. Brown, H. A. Tran, S. D. Chunilal. Weight-based enoxaparin dosing for venous thromboembolism (VTE) in obesity gives similar anti-Xa levels to patients <100kg, with no increase in major bleeding. Semin Thromb Hemost 2019; 45:94–99.
- Tran HA, Gibbs H. et al., The Diagnosis and Treatment of Venous Thromboembolism – A guideline Summary on behalf of Thrombosis & Haemostasis Society of Australia and New Zealand. Med J Aust. 2019 Mar;210(5):227-235. (top 10 most downloaded 2019)
- John J, Dunkley S, Lam J, Tran HA, Srivastava A. Principles of haemophilia care: The asia pacific perspective: Response. Haemophilia. ePub Aug 24 2018
- Lim M, Indran T, Cummins A, Bennett A, Wood E, Brown S, McQuilten Z, Tran HA, Chan N, Chunilal S. Utility of a Nurse-Led Pathway for patients with acute venous thromboembolism discharged on rivaroxaban: a prospective study. J Thromb Thrombolysis 2019; 1-8.
- Stevens H & Tran HA. An Update on Diagnosis and Anticoagulant Therapy for Venous Thromboembolism in Australia. Intern Med J. 2018 Oct;48(10):1175-1184. (top 10 most downloaded 2019)
- Bortz H, Correlo C, Tran HA. Increasing understanding regarding the risk of concomitant use of carbamazepine and Direct Oral Anticoagulants (DOACs). Journal of Pharmacy Practice. ePub July 11, 2018. 2019 32 (2), 123-125
- Brazilek R, Tovar-Lopez F, Wong A, Tran HA, Davis A, McFadyen J, Kaplan Z, Chunilal S, Jackson S, Mitchell A, Nesbitt W. Application of a strain rate gradient microfluidic device to von Willebrand disease screening. Lab Chip. 2017 Jul 25;17(15):2595-2608.
- Mason JA, Parikh S, Tran HA, Rowell J, McRae S. Australian multicentre study of current real-world prophylaxis practice in severe and moderate haemophilia A and B. Haemophilia. 2018 Mar;24(2):253-260
- Dunkley S, Lam JCM, John MJ, Wong RSM, Tran HA, Nair SC, Shima M, Street A, Srivastava A for the Asia Pacific Haemophilia Working Group (APHWG). Principles of haemophilia care: the Asia-Pacific perspective. Haemophilia. 2018;24:366–375
- Ratnasingam S, Walker T.A, Tran H., Kaplan ZS, McFadyen J, Tran HAM, The TS, Fleming S, Catalano JV, Chunilal S, Johnston A, Opat SS, Shortt J. Bortezomib-Based Antibody Depletion for Refractory Autoimmune Hematological Diseases. Blood Advances. 2016 1(1):31-5.
- Lukito P, Collecutt M, Dauer R, Morgan S, Tran HA. Utilising a hybrid anti-Xa calibration assay in unfractionated heparin (UFH) monitoring: validation of assay and its correlation with activated partial thromboplastin time (aPTT). Pathology 2016 48(5):501-3.
- McQuilten Z, Aubron C, Bailey M, Board J, Buhr J, Dennis M, Forrest P, McIlroy D, Murray L, Murphy D, Pellegrino V, Pilcher D, Sheldrake J, Tran HA, Vallance S, Cooper DJ. Low-dose heparin in critically ill patients undergoing extracorporeal membrane oxygenation-the help-ECMO pilot randomised controlled trial. Blood 2016;128(22):3822-
- McFadyen J, Kaplan Z, Tran HAM. Factor VIII Inhibitor Eradication with Bortezomib in Acquired Haemophilia A. Br J Haematol. 2016 Jul 19. doi: 10.1111/bjh.14185.
Professional Appointments
Head of Thrombosis and Haemostasis Services, Alfred Health
Director, Ronald Sawers Haemophilia Treatment Centre, Alfred Health
Clinical Professor at the Australian Centre for Blood Diseases (ACBD), Central Clinical School, Monash University
Chair, Clinical Trials Group, Thrombosis and Haemostasis Society of Australia and New Zealand (THANZ)
Chair of the Gene and Novel Therapies (GETS) committee, Australian Haemophilia Clinical Directors Organisation (AHCDO
Presentations (Selected from 2021)
Australian New Zealand Headache Society Annual Scientific Meeting.
Thrombosis with Thrombocytopenia Syndrome and CVST. November 21st 2021.
Haemophilia Foundation Australia 20th Congress. October 8-9, 2021.
Brief overview of the Australian experience – spectrum of changes in bleeding disorders over the years since the introduction of recombinant factors.
Blood Scientific Congress Adelaide Australia.
Vaccine-Induced Thrombotic Thrombocytopenia (VITT) – the Australian experience. September 21 2021.
Royal Australian and New Zealand College of Radiologists annual congress.
Direct Oral anticoagulants Updates. September 18th 2021.
AustralAsian Stroke Academy. Hunter Medical Research Institute in Newcastle NSW from 5th to 6th June 2021.
Latest updates on Vaccine associated thrombosis and other clotting disorders in stroke.
Annual Scientific Meeting (ASM) of the Australian and New Zealand College of Anaesthetists (ANZCA) and Faculty of Pain Medicine (FPM), from April 27 to May 4, 2021.
NOACs and anaesthesia / haematology update
STOP CAT: Selecting Treatment Options for Patients with Cancer-Associated Thrombosis. VTE webinar. Singapore April 15, 2021.
Research Grant Awards 2021
MRFF – NHMRC
A national, multi-centre study evaluating Thrombotic Thrombocytopenia Syndrome (TTS) associated with ChAdOx1 (AZD1222) and other SARS-CoV-2 vaccines (viral vector and m-RNA) (2021 – 23 APP 2015305) $ 2.9M
Professional Memberships
- Thrombosis Haemostasis Society of Australia & New Zealand (THANZ)
- International Society of Thrombosis and Haemostasis (ISTH)
- Australian Haemophilia Centre Directors’ Organisation (AHCDO)
- World Federation of Haemophilia (WFH)
- Asia Pacific Society of Thrombosis & Hemostasis (APSTH)
- Haematology Society of Australasia and New Zealand (HSANZ)
- European Haematology Association (EHA)
Fellow of the Royal College of Pathologists of Australia (FRCPA)
Fellow of Royal Australasian College of Physicians (FRACP)
Media Appearances
Thrombotic Thrombocytopenia Syndrome associated with AstraZeneca COVID-19 vaccine
- 3AW radio Melbourne May 7 2021
- 7News May 7 2021
- The Age newspaper, June 7 2021. ‘We can treat it’: Mortality rate of rare condition linked to AstraZeneca shot plunges
[VIEW: https://www.smh.com.au/national/we-can-treat-it-mortality-rate-of-rare-condition-linked-to-astrazeneca-shot-plunges-20210607-p57yod.html ] - ABC Radio Melbourne Australia June 8 2021
- ABC News24 Australia June 8 2021
- Nine News Australia June 8 2021
- The Project, Network TEN Australia June 8 2021
- Four Corners, ABC News June 14 2021
- ABC News, September 25 2021 Early detection, treatment behind lower rate of mortality from rare AstraZeneca-related clots.
[VIEW: https://www.abc.net.au/news/2021-09-25/low-mortality-rate-astrazeneca-covid-vaccine-clots-tts/100489408] - The Guardian, October 2 2021. “Just in time”: how Australian doctors drastically reduced deaths from vaccine-linked blood clots.
[VIEW: https://www.theguardian.com/australia-news/2021/oct/02/just-in-time-how-australian-doctors-drastically-reduced-deaths-from-vaccine-linked-blood-clots ]
Launch of Venous thromboembolism Prevention Clinical Standards October 2018
- 3AW Radio
